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A ‘Game Changer’ For Organ Transplants: Blood Type of Donor Kidneys Altered in Breakthrough Research_我的网站

一 |     Breakthrough new research could significantly increase supply of organs for people with rarer blood types waiting for a transplant, reported The Guardian.,A team of scientists from the University of Cambridge have successfully altered the blood type of three donor kidneys. By flushing blood infused with a special enzyme through a human kidney the scientists removed the blood type markers lining the blood vessels of the organ.,The procedure required using a device that is connected with a donor’s kidney to pass oxygenated blood through it - a normothermic perfusion machine. As a result, the organ was converted to type O, considered the universal donor.,Blood Group Compatible,As the blood type of a donor must be compatible with the recipient’s, the new development could increase the supply of kidneys available for transplant.,A kidney from someone with blood type A cannot be transplanted to someone with blood type B, or visa versa. In such a case, the receiving body’s immune system would reject the new organ, interpreting the different blood type as foreign.,So changing the blood type to the universal O would mean the donor organ could be used for people with any blood type.,“Our confidence was really boosted after we applied the enzyme to a piece of human kidney tissue and saw very quickly that the antigens were removed. After this, we knew that the process is feasible, and we just had to scale up the project to apply the enzyme to full-size human kidneys,” Serena MacMillan, a PhD student at the University of Cambridge, said.,Scientists involved in the research, funded by charity Kidney Research UK and due to be published in the British Journal of Surgery, clarified that the outcome might have particular implications for minority ethnic groups.,Science & TechGood News for ABs: Scientists Can Now Change People's Blood Type21 February, 16:34 GMT,Some blood groups such as O Rh positive and B Rh positive are more prevalent among black, Asian and minority ethnic communities. To complicate matters further, some rare blood types are only found within the black, Asian and minority ethnic communities,This typically places them at a disadvantage, as they struggle to find a match. With low donation rates from these populations, stressed the researchers, sometimes such patients wait for as long as over a year for a compatible donor. They cited figures from 2020-21 showing that just over 9% of total organ donations in the UK came from black and minority ethnic donors. On the other hand, black and minority ethnic patients make up 33% of the kidney transplant waiting list.,“It’s very exciting to think about how this could potentially impact so many lives,” added Serena MacMillan.,The “potentially gamechanging” research was applauded by Dr Aisling McMahon, the executive director of research at Kidney Research UK.,The scientists will now test the reintroduction of other blood types and observe how the novel approach in clinical settings.。    

直播吧4月21日讯 在2-1逆转富勒姆后，切尔西后卫科尔维尔表示，球队上半场的表现不够好。

二 |

科尔维尔这样谈道：“我真的很高兴球队赢下胜利，最后和球迷一起庆祝的感觉是很特别的。我们为球迷们拼尽了全力，所以看到他们最后高高兴兴回家，感觉很棒。无论如何，在赛季的这个阶段，这对我们来说是一场重要的胜利。”

“考虑到这是一场同城德比，考虑到两支球队之间的激烈竞争，这意义就更重大了。这对我们来说意味着很多，特别是内托的进球让我们锁定了胜局，最后能和球迷们一起庆祝，这感觉真的很特别。这也让我们继续努力竞争前四，竞争欧冠资格，这是每个人都渴望的，像切尔西这样的俱乐部应该参加最好的赛事。”

“我们都知道，球队上半场的表现不够好，所以，在下半场，我们知道必须全力以赴，展现出我们多渴望赢得胜利。我认为下半场你们看到的是一支完全不同的切尔西，这正是我们需要在每场比赛开始都拿出的表现。”

“这对我们来说是一场重要的胜利，因为客场挑战富勒姆从不容易。

三 | 这绝对能让我们在接下来的比赛中充满信心，无论是联赛还是欧战，但我们必须认真对待每一场比赛。现在我们的焦点是下一场对阵埃弗顿，这是一场艰难的比赛，但有了这场胜利，我们可以带着信心投入比赛。

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